Statements (133)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:Beckwith-Wiedemann_syndrome gptkb:Silver-Russell_syndrome |
| gptkbp:biologicalProcess |
cell differentiation
cell proliferation embryonic development growth regulation metabolic regulation |
| gptkbp:Entrez_Gene_ID |
3481
ENSG00000167244 |
| gptkbp:fullName |
gptkb:Insulin-like_growth_factor_2
|
| gptkbp:function |
growth factor
fetal development regulation of cell growth |
| gptkbp:gene |
gptkb:IGF2
IGF2 (human gene) |
| gptkbp:HGNC_ID |
5466
|
| https://www.w3.org/2000/01/rdf-schema#label |
human IGF2
|
| gptkbp:imprintingStatus |
imprinted (expressed from paternal allele)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11p15.5
|
| gptkbp:maturePeptideLength |
67 amino acids
|
| gptkbp:molecularWeight |
7.5 kDa (mature peptide)
|
| gptkbp:OMIM |
147470
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1IGL
2V7O 1IGT 2V5P 2V5Q 2V5R 2V5S 2V5T 2V5U 2V5V 2V5W 2V5X 2V5Y 2V5Z 2V60 2V61 2V62 2V63 2V64 2V65 2V66 2V67 2V68 2V69 2V6A 2V6B 2V6C 2V6D 2V6E 2V6F 2V6G 2V6H 2V6I 2V6J 2V6K 2V6L 2V6M 2V6N 2V6O 2V6P 2V6Q 2V6R 2V6S 2V6T 2V6U 2V6V 2V6W 2V6X 2V6Y 2V6Z 2V70 2V71 2V72 2V73 2V74 2V75 2V76 2V77 2V78 2V79 2V7A 2V7B 2V7C 2V7D 2V7E 2V7F 2V7G 2V7H 2V7I 2V7J 2V7K 2V7L 2V7M 2V7N 2V7P 2V7Q 2V7R 2V7S 2V7T 2V7U 2V7V 2V7W 2V7X 2V7Y 2V7Z |
| gptkbp:postTranslationalModification |
glycosylation
proteolytic processing |
| gptkbp:recipient |
gptkb:INSR
gptkb:IGF2R gptkb:IGF1R |
| gptkbp:relatedTo |
gptkb:IGF1
gptkb:insulin |
| gptkbp:sequence |
180 amino acids (precursor)
|
| gptkbp:structure |
single-chain polypeptide
|
| gptkbp:tissue_specificity |
gptkb:skeletal_muscle
gptkb:adrenal_gland gptkb:kidney gptkb:placenta gptkb:testis brain liver pancreas fetal tissues |
| gptkbp:UniProtID |
P01344
|
| gptkbp:bfsParent |
gptkb:mouse_Igf2
gptkb:rat_Igf2 |
| gptkbp:bfsLayer |
8
|