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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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HNRPK
heterogeneous nuclear ribonucleoprotein K
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gptkbp:associatedWith
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gptkb:cancer
leukemia
neurodegenerative diseases
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gptkbp:discoveredBy
|
1980s
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gptkbp:domain
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gptkb:KH_domain
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gptkbp:encodedBy
|
HNRNPK gene
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gptkbp:expressedIn
|
many tissues
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gptkbp:fullName
|
Heterogeneous nuclear ribonucleoprotein K
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gptkbp:function
|
signal transduction
regulation of gene expression
RNA binding
mRNA processing
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gptkbp:gene
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gptkb:HNRNPK
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|
https://www.w3.org/2000/01/rdf-schema#label
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hnRNP K
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gptkbp:interactsWith
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gptkb:Fyn
gptkb:gene
gptkb:p53
gptkb:c-Src
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gptkbp:locatedOnChromosome
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gptkb:9q21.32
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gptkbp:location
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gptkb:nucleus
gptkb:cytoplasm
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gptkbp:molecularWeight
|
~65 kDa
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gptkbp:mutationAssociatedWith
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gptkb:acute_myeloid_leukemia
intellectual disability
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gptkbp:organism
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gptkb:Homo_sapiens
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gptkbp:orthologIn
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gptkb:mouse
gptkb:zebrafish
gptkb:Drosophila_melanogaster
right
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gptkbp:overexpressedIn
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gptkb:testis
brain
liver
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gptkbp:postTranslationalModification
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phosphorylation
sumoylation
acetylation
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gptkbp:regulates
|
apoptosis
translator
DNA repair
transcription
cell cycle
splicing
chromatin remodeling
signal transduction pathways
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gptkbp:structure
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contains three KH domains
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gptkbp:UniProtID
|
P61978
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gptkbp:bfsParent
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gptkb:RRM_domain
gptkb:hnRNP_proteins
gptkb:hnRNPs
gptkb:HNRNPK
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gptkbp:bfsLayer
|
7
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