gamma-aminobutyric acid (GABA)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:amino_acid_transporter gptkb:neurotransmitter
gptkbp:actsOn	gptkb:GABA_A_receptor gptkb:GABA_B_receptor gptkb:GABA_C_receptor
gptkbp:biosynthesized_from	gptkb:glutamic_acid
gptkbp:CASNumber	56-12-2
gptkbp:chemicalFormula	C4H9NO2
gptkbp:decreased_by	stress caffeine
gptkbp:discoveredBy	gptkb:Eugene_Roberts 1950
gptkbp:enzyme_for_synthesis	gptkb:glutamate_decarboxylase
gptkbp:foundIn	gptkb:Bacteria invertebrates plants vertebrates central nervous system
gptkbp:function	inhibitory neurotransmitter
gptkbp:increased_by	gptkb:beer gptkb:benzodiazepines barbiturates
gptkbp:isomerOf	gptkb:beta-aminobutyric_acid
gptkbp:IUPACName	gptkb:4-aminobutanoic_acid
gptkbp:MeSH_ID	D005737
gptkbp:metabolism	gptkb:GABA_transaminase
gptkbp:molecularWeight	103.12 g/mol
gptkbp:pKa	10.43 4.23
gptkbp:predecessor	glutamate
gptkbp:PubChem_CID	119 CHEBI:16865
gptkbp:role	gptkb:synaptic_plasticity epilepsy pain modulation learning and memory neurodevelopment anxiety regulation sleep regulation movement control mood regulation muscle tone regulation
gptkbp:solubility	very soluble
gptkbp:UNII	Y5F674LQ8E
gptkbp:usedFor	gptkb:dietary_supplement
gptkbp:bfsParent	gptkb:SLC6A13 gptkb:GABAA-rho_receptor gptkb:GABA_A-rho_receptor
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	gamma-aminobutyric acid (GABA)