|
gptkbp:instanceOf
|
gptkb:protein
ion channel
|
|
gptkbp:alsoKnownAs
|
gptkb:GABA_C_receptor
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:effect
|
hyperpolarization of neuron membrane
|
|
gptkbp:encodedBy
|
gptkb:GABRR1
gptkb:GABRR2
gptkb:GABRR3
|
|
gptkbp:enemyOf
|
gptkb:GABA
gptkb:TPMPA
cis-4-aminocrotonic acid (CACA)
|
|
gptkbp:expressedIn
|
high in retina
low in brain
|
|
gptkbp:function
|
mediates inhibitory neurotransmission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GABA A-rho receptor
|
|
gptkbp:ligand
|
gptkb:gamma-aminobutyric_acid_(GABA)
|
|
gptkbp:location
|
retina
central nervous system
|
|
gptkbp:modulatedBy
|
gptkb:picrotoxin
gptkb:pregnenolone_sulfate
|
|
gptkbp:permeableTo
|
chloride ions
|
|
gptkbp:pharmacology
|
insensitive to benzodiazepines
insensitive to bicuculline
|
|
gptkbp:proteinFamily
|
gptkb:Cys-loop_receptor_family
|
|
gptkbp:role
|
visual processing
inhibitory synaptic transmission
|
|
gptkbp:structure
|
pentameric
|
|
gptkbp:subclassOf
|
gptkb:GABA_A_receptor
|
|
gptkbp:subunit
|
rho1
rho2
rho3
|
|
gptkbp:bfsParent
|
gptkb:GABA_C_receptor
|
|
gptkbp:bfsLayer
|
6
|