Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:4-aminobutyrate_aminotransferase
|
| gptkbp:associatedWith |
gptkb:GABA-transaminase_deficiency
epilepsy (when deficient) |
| gptkbp:biologicalProcess |
aminotransferase activity
neurotransmitter catabolic process |
| gptkbp:CASNumber |
9029-11-2
|
| gptkbp:catalyzes |
conversion of GABA to succinic semialdehyde
|
| gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
| gptkbp:EC_number |
gptkb:2.6.1.19
|
| gptkbp:encodedBy |
gptkb:ABAT_gene
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
GABA degradation
|
| gptkbp:GO_term |
gptkb:GO:0004352
|
| https://www.w3.org/2000/01/rdf-schema#label |
GABA transaminase
|
| gptkbp:inhibitedBy |
gptkb:vigabatrin
|
| gptkbp:locatedOnChromosome |
gptkb:16p13.2_(human_ABAT_gene)
|
| gptkbp:pathway |
gptkb:GABA_shunt
|
| gptkbp:presentIn |
gptkb:Bacteria
animals humans plants |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:gamma-aminobutyric_acid
|
| gptkbp:UniProtID |
P80404 (human)
|
| gptkbp:bfsParent |
gptkb:GABA
|
| gptkbp:bfsLayer |
5
|