|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:ATCCode
|
gptkb:N05BA
|
|
gptkbp:broadcastOn
|
controlled substance
|
|
gptkbp:category
|
benzodiazepine
sedative
anticonvulsant
muscle relaxant
hypnotic
|
|
gptkbp:cause
|
tolerance
withdrawal symptoms
falls in elderly
paradoxical reactions
psychomotor impairment
|
|
gptkbp:chemicalFormula
|
fusion of benzene and diazepine rings
|
|
gptkbp:contraindication
|
pregnancy
history of substance abuse
|
|
gptkbp:discoveredBy
|
gptkb:Leo_Sternbach
|
|
gptkbp:example
|
gptkb:lorazepam
gptkb:clonazepam
gptkb:diazepam
gptkb:temazepam
alprazolam
|
|
gptkbp:excretion
|
kidneys
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
benzodiazepines
|
|
gptkbp:interactsWith
|
gptkb:beer
opioids
barbiturates
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1960
|
|
gptkbp:mechanismOfAction
|
enhance GABA-A receptor activity
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:overdoseTreatment
|
gptkb:flumazenil
|
|
gptkbp:riskFactor
|
addiction
cognitive impairment
overdose
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:shouldNotBeCombinedWith
|
gptkb:CNS_depressants
|
|
gptkbp:sideEffect
|
confusion
drowsiness
respiratory depression
dependence
memory impairment
|
|
gptkbp:usedFor
|
insomnia
anxiety disorders
seizure disorders
muscle spasms
alcohol withdrawal
|
|
gptkbp:bfsParent
|
gptkb:GABA
gptkb:G_protein-coupled_receptor
|
|
gptkbp:bfsLayer
|
5
|