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gptkbp:instanceOf
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neurotransmitter
amino acid transporter
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gptkbp:abbreviation
|
gptkb:GABA
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gptkbp:actsOn
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gptkb:GABA_A_receptor
gptkb:GABA_B_receptor
gptkb:GABA_C_receptor
|
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gptkbp:biosynthesized_from
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gptkb:glutamate_decarboxylase
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gptkbp:catabolized_by
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gptkb:GABA_transaminase
|
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gptkbp:chemicalFormula
|
C4H9NO2
|
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gptkbp:discoveredBy
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gptkb:Eugene_Roberts
|
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gptkbp:discoveredIn
|
1950
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gptkbp:foundIn
|
animals
plants
central nervous system
microorganisms
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gptkbp:function
|
inhibitory neurotransmitter
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
gamma-aminobutyric acid
|
|
gptkbp:IUPACName
|
gptkb:4-aminobutanoic_acid
|
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gptkbp:meltingPoint
|
203 °C
|
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gptkbp:molecularWeight
|
103.12 g/mol
|
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gptkbp:predecessor
|
glutamate
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gptkbp:related_disorder
|
gptkb:depression
epilepsy
anxiety
|
|
gptkbp:relatedTo
|
gptkb:gabapentin
gptkb:vigabatrin
gptkb:benzodiazepines
barbiturates
|
|
gptkbp:role_in_animals
|
neural inhibition
|
|
gptkbp:role_in_brain
|
reduces neuronal excitability
|
|
gptkbp:role_in_humans
|
pain modulation
cognitive function
auditory processing
muscle relaxation
motor control
sedation
anticonvulsant effect
anxiolytic effect
sleep regulation
visual processing
endocrine regulation
immune modulation
memory formation
mood regulation
|
|
gptkbp:role_in_plants
|
metabolism regulation
stress response
|
|
gptkbp:solubility
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gptkb:water
|
|
gptkbp:bfsParent
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gptkb:GABA
gptkb:G_protein-coupled_receptor
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gptkbp:bfsLayer
|
5
|