|
gptkbp:instanceOf
|
gptkb:chemical_compound
neurotransmitter
|
|
gptkbp:actsOn
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:biosynthesized_from
|
gptkb:glutamic_acid_decarboxylase
|
|
gptkbp:CASNumber
|
56-12-2
|
|
gptkbp:category
|
neurotransmitter
amino acid transporter
biogenic amine
inhibitory neurotransmitter
non-protein amino acid
|
|
gptkbp:chemicalFormula
|
C4H9NO2
|
|
gptkbp:discoveredBy
|
gptkb:Eugene_Roberts
|
|
gptkbp:discoveredIn
|
1950
|
|
gptkbp:effect
|
anticonvulsant effect
anxiolytic effect
hyperpolarization of neurons
muscle relaxant effect
reduced neuronal excitability
sedative effect
|
|
gptkbp:enemyOf
|
gptkb:bicuculline
gptkb:muscimol
|
|
gptkbp:foundIn
|
animals
plants
central nervous system
microorganisms
|
|
gptkbp:fullName
|
gptkb:gamma-aminobutyric_acid
|
|
gptkbp:function
|
inhibitory neurotransmitter
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GABA
|
|
gptkbp:inhibitedBy
|
gptkb:bicuculline
|
|
gptkbp:IUPACName
|
gptkb:4-aminobutanoic_acid
|
|
gptkbp:metabolism
|
gptkb:GABA_transaminase
|
|
gptkbp:molecularWeight
|
103.12 g/mol
|
|
gptkbp:predecessor
|
glutamate
|
|
gptkbp:recipient
|
gptkb:GABA_A_receptor
gptkb:GABA_B_receptor
gptkb:GABA_C_receptor
|
|
gptkbp:relatedTo
|
gptkb:beer
gptkb:gabapentin
gptkb:vigabatrin
gptkb:benzodiazepines
barbiturates
|
|
gptkbp:role
|
epilepsy
muscle relaxation
anxiety regulation
sleep regulation
|
|
gptkbp:solubility
|
gptkb:water
|
|
gptkbp:usedAs
|
dietary supplement
|
|
gptkbp:bfsParent
|
gptkb:GBAR
|
|
gptkbp:bfsLayer
|
4
|