|
gptkbp:instanceOf
|
gptkb:drug
anticonvulsant
|
|
gptkbp:approvalYear
|
2009 (US)
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
N03AG04
|
|
gptkbp:brand
|
gptkb:Sabril
|
|
gptkbp:CASNumber
|
60643-86-9
|
|
gptkbp:category
|
GABA analogues
antiepileptic drugs
|
|
gptkbp:chemicalFormula
|
C4H9NO2
|
|
gptkbp:contraindication
|
history of visual field defects
|
|
gptkbp:discoveredBy
|
gptkb:Richard_H._Silverman
|
|
gptkbp:eliminationHalfLife
|
5-8 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
vigabatrin
|
|
gptkbp:improves
|
GABA levels in the brain
|
|
gptkbp:isomerOf
|
racemic mixture
|
|
gptkbp:KEGGID
|
D08668
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
irreversible inhibitor of GABA transaminase
|
|
gptkbp:MedlinePlusID
|
a698012
|
|
gptkbp:metabolism
|
renal excretion
|
|
gptkbp:molecularWeight
|
103.12 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
5665
CHEMBL1425
DB01071
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
confusion
fatigue
weight gain
drowsiness
visual field loss
|
|
gptkbp:synonym
|
gptkb:gamma-vinyl-GABA
|
|
gptkbp:UNII
|
H7900806Z3
|
|
gptkbp:usedFor
|
epilepsy
infantile spasms
refractory complex partial seizures
|
|
gptkbp:bfsParent
|
gptkb:GABA
|
|
gptkbp:bfsLayer
|
5
|