Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Biology
|
| gptkbp:can_transform_into |
fibrinogen to fibrin
|
| gptkbp:function |
catalyzes the conversion of prothrombin to thrombin
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor Xa
|
| gptkbp:initiated_by |
gptkb:factor_X
gptkb:antithrombin gptkb:factor_IXa gptkb:factor_VIIa gptkb:rivaroxaban gptkb:apixaban gptkb:edoxaban thrombin |
| gptkbp:interacts_with |
factor V
|
| gptkbp:involved_in |
blood coagulation
|
| gptkbp:is_activated_in |
bloodstream
|
| gptkbp:is_essential_for |
hemostasis
|
| gptkbp:is_involved_in |
gptkb:deep_vein_thrombosis
biomarker discovery diagnostic assays drug development laboratory testing therapeutic interventions surgical procedures clinical research wound healing cardiovascular diseases anticoagulation therapy patient management pulmonary embolism venous thromboembolism coagulation disorders stroke prevention trauma response platelet activation fibrinolysis thrombin generation atrial fibrillation management thromboembolic disorders hemophilia treatment antithrombotic therapy thrombus formation clot formation coagulation factor activation ischemic events vascular injury response |
| gptkbp:is_part_of |
intrinsic pathway of coagulation
extrinsic pathway of coagulation |
| gptkbp:is_regulated_by |
protein C
protein S |
| gptkbp:is_targeted_at |
direct oral anticoagulants
|
| gptkbp:located_in |
blood plasma
|
| gptkbp:measures |
anti-Xa assay
|
| gptkbp:produced_by |
liver
activated factor X |
| gptkbp:role |
plays a key role in the coagulation cascade
|
| gptkbp:bfsParent |
gptkb:factor_X
|
| gptkbp:bfsLayer |
6
|