Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedFrom |
gptkb:factor_VII
|
| gptkbp:alternativeName |
activated factor VII
|
| gptkbp:CAS_number |
93481-97-1
|
| gptkbp:cofactor |
tissue factor
|
| gptkbp:EC_number |
3.4.21.21
|
| gptkbp:encodedBy |
F7 gene
|
| gptkbp:function |
initiates blood coagulation
activates factor IX activates factor X |
| https://www.w3.org/2000/01/rdf-schema#label |
factor VIIa
|
| gptkbp:inhibitedBy |
gptkb:tissue_factor_pathway_inhibitor
gptkb:antithrombin_III |
| gptkbp:location |
blood plasma
|
| gptkbp:medicalUse |
NovoSeven
Sevenfact |
| gptkbp:MeSH_ID |
D005192
|
| gptkbp:molecularWeight |
50 kDa
|
| gptkbp:OMIM |
613878
|
| gptkbp:producedBy |
liver
|
| gptkbp:structure |
gptkb:serine_protease
|
| gptkbp:UniProtID |
P08709
|
| gptkbp:usedAsDrug |
gptkb:recombinant_factor_VIIa
|
| gptkbp:usedFor |
treatment of hemophilia
treatment of bleeding disorders |
| gptkbp:bfsParent |
gptkb:factor_X
gptkb:factor_VII |
| gptkbp:bfsLayer |
6
|