|
gptkbp:instanceOf
|
gptkb:protein
gptkb:serine_protease
|
|
gptkbp:activatedBy
|
gptkb:heparin
|
|
gptkbp:alternativeName
|
gptkb:antithrombin
gptkb:ATIII
gptkb:SERPINC1
|
|
gptkbp:category
|
gptkb:anticoagulant
serpin family
|
|
gptkbp:clinicalTrialPhase
|
antithrombin activity assay
|
|
gptkbp:deficiencyCauses
|
increased risk of thrombosis
|
|
gptkbp:deficiencyType
|
hereditary
acquired
|
|
gptkbp:discoveredBy
|
Olaf Hammarsten
|
|
gptkbp:discoveredIn
|
1905
|
|
gptkbp:encodedBy
|
gptkb:SERPINC1_gene
|
|
gptkbp:expressedIn
|
liver
|
|
gptkbp:foundIn
|
human blood plasma
|
|
gptkbp:function
|
regulation of blood coagulation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
antithrombin III
|
|
gptkbp:inhibitedBy
|
gptkb:factor_IXa
gptkb:factor_Xa
gptkb:thrombin
gptkb:factor_XIIa
gptkb:factor_XIa
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q25.1
|
|
gptkbp:molecularWeight
|
58 kDa
|
|
gptkbp:OMIM
|
107300
|
|
gptkbp:PDB
|
2ANT
|
|
gptkbp:structure
|
gptkb:protein
|
|
gptkbp:UniProtID
|
P01008
|
|
gptkbp:usedIn
|
diagnosis of coagulation disorders
|
|
gptkbp:bfsParent
|
gptkb:factor_VIIa
gptkb:Factor_VIIa
gptkb:Factor_Xa
gptkb:antithrombin
gptkb:factor_IXa
gptkb:factor_Xa
gptkb:serpins
gptkb:factor_XIa
|
|
gptkbp:bfsLayer
|
7
|