Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
blood coagulation factor |
| gptkbp:activatedBy |
gptkb:factor_Xa
gptkb:thrombin |
| gptkbp:associatedWith |
gptkb:factor_V_deficiency
factor V Leiden |
| gptkbp:complexes_with |
gptkb:factor_Xa
lipoprotein calcium ions |
| gptkbp:EC_number |
3.4.21.5
|
| gptkbp:function |
cofactor in prothrombinase complex
accelerates conversion of prothrombin to thrombin |
| gptkbp:gene |
F5
|
| gptkbp:halfLife |
minutes (short-lived)
|
| https://www.w3.org/2000/01/rdf-schema#label |
factor Va
|
| gptkbp:inhibitedBy |
protein S
activated protein C |
| gptkbp:is_activated_form_of |
factor V
|
| gptkbp:locatedOnChromosome |
chromosome 1q24
|
| gptkbp:location |
gptkb:plasma
|
| gptkbp:molecularWeight |
~330 kDa
|
| gptkbp:role_in_coagulation_cascade |
procoagulant
|
| gptkbp:significance |
bleeding disorders
thrombophilia |
| gptkbp:species |
gptkb:human
mammals |
| gptkbp:structure |
heterodimer of heavy and light chains
|
| gptkbp:bfsParent |
gptkb:factor_II
|
| gptkbp:bfsLayer |
6
|