dual specificity phosphatase 4

URI: https://gptkb.org/entity/dual_specificity_phosphatase_4
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alias gptkb:PAC-1
gptkb:MKP-2
gptkbp:associatedWith gptkb:cancer
inflammatory diseases
gptkbp:biologicalProcess protein tyrosine phosphatase activity
protein serine/threonine phosphatase activity
gptkbp:encodedBy DUSP4 gene
gptkbp:Entrez_Gene_ID ENSG00000120071
gptkbp:expressedIn various tissues
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function dephosphorylation of MAP kinases
gptkbp:gene gptkb:DUSP4
gptkbp:HGNC_ID 3070
https://www.w3.org/2000/01/rdf-schema#label dual specificity phosphatase 4
gptkbp:involves signal transduction
negative regulation of cell proliferation
cellular response to stress
gptkbp:length 384
gptkbp:locatedOnChromosome gptkb:8p12
gptkbp:location gptkb:nucleus
gptkbp:molecularWeight 42 kDa
gptkbp:OMIM 601135
gptkbp:proteinFamily gptkb:dual_specificity_phosphatase_family
gptkbp:RefSeq NM_001394
gptkbp:regulates gptkb:ERK1
gptkb:ERK2
gptkb:MAPK/ERK_pathway
gptkb:JNK
gptkb:p38_MAPK
gptkbp:UniProtID gptkb:Q13115
gptkbp:bfsParent gptkb:DUSP4
gptkbp:bfsLayer 7