Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
peptide
|
gptkbp:binds |
gptkb:delta-opioid_receptor
gptkb:mu-opioid_receptor opioid |
gptkbp:category |
gptkb:endogenous_opioid_peptide
|
gptkbp:containsAminoAcidSequence |
Tyr-Gly-Gly-Phe-Leu
Tyr-Gly-Gly-Phe-Met |
gptkbp:degradedBy |
enkephalinase
|
gptkbp:discoveredBy |
gptkb:John_Hughes
gptkb:Hans_Kosterlitz |
gptkbp:discoveredIn |
1975
|
gptkbp:foundIn |
gptkb:spinal_cord
gptkb:adrenal_medulla brain gut |
gptkbp:function |
pain modulation
inhibits neurotransmitter release |
gptkbp:hasMolecularFormula |
C27H35N5O7 (met-enkephalin)
C28H37N5O7 (leu-enkephalin) |
https://www.w3.org/2000/01/rdf-schema#label |
enkephalin
|
gptkbp:predecessor |
gptkb:proopiomelanocortin
proenkephalin |
gptkbp:relatedTo |
gptkb:endorphin
gptkb:dynorphin |
gptkbp:role |
analgesia
stress response immune modulation |
gptkbp:subspecies |
leu-enkephalin
met-enkephalin |
gptkbp:type |
pentapeptide
|
gptkbp:bfsParent |
gptkb:CREB_(cAMP_response_element-binding_protein)
gptkb:delta-opioid_receptor |
gptkbp:bfsLayer |
7
|