Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:peptide
|
| gptkbp:binds |
gptkb:opioid
gptkb:delta-opioid_receptor gptkb:mu-opioid_receptor |
| gptkbp:category |
gptkb:endogenous_opioid_peptide
|
| gptkbp:containsAminoAcidSequence |
Tyr-Gly-Gly-Phe-Leu
Tyr-Gly-Gly-Phe-Met |
| gptkbp:degradedBy |
enkephalinase
|
| gptkbp:discoveredBy |
gptkb:John_Hughes
gptkb:Hans_Kosterlitz |
| gptkbp:discoveredIn |
1975
|
| gptkbp:foundIn |
gptkb:spinal_cord
gptkb:adrenal_medulla brain gut |
| gptkbp:function |
pain modulation
inhibits neurotransmitter release |
| gptkbp:hasMolecularFormula |
C27H35N5O7 (met-enkephalin)
C28H37N5O7 (leu-enkephalin) |
| gptkbp:predecessor |
gptkb:proopiomelanocortin
proenkephalin |
| gptkbp:relatedTo |
gptkb:endorphin
gptkb:dynorphin |
| gptkbp:role |
analgesia
stress response immune modulation |
| gptkbp:subspecies |
leu-enkephalin
met-enkephalin |
| gptkbp:type |
pentapeptide
|
| gptkbp:bfsParent |
gptkb:CREB_(cAMP_response_element-binding_protein)
gptkb:delta-opioid_receptor |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
enkephalin
|