cytochrome P450 reductase

URI: https://gptkb.org/entity/cytochrome_P450_reductase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:alternativeName	gptkb:CPR CYPOR NADPH-cytochrome P450 oxidoreductase
gptkbp:catalyzes	NADPH + 2 ferricytochrome c → NADP+ + 2 ferrocytochrome c + H+
gptkbp:cofactor	gptkb:FMN gptkb:FAD NADPH
gptkbp:EC_number	1.6.2.4
gptkbp:expressedIn	gptkb:thyroid gptkb:cancer gptkb:skin gptkb:pituitary_gland gptkb:skeletal_muscle gptkb:adrenal_gland gptkb:kidney gptkb:placenta gptkb:prostate gptkb:small_intestine gptkb:testis gptkb:thymus brain heart liver spleen bone marrow colon esophagus lymph node pancreas salivary gland stomach
gptkbp:foundIn	gptkb:endoplasmic_reticulum
gptkbp:function	electron transfer
gptkbp:gene	POR
https://www.w3.org/2000/01/rdf-schema#label	cytochrome P450 reductase
gptkbp:interactsWith	gptkb:cytochrome_P450
gptkbp:locale	microsomal
gptkbp:locatedOnChromosome	7q11.23
gptkbp:molecularWeight	~77 kDa
gptkbp:mutationAssociatedWith	gptkb:Antley-Bixler_syndrome disordered steroidogenesis
gptkbp:PDB	1AMO
gptkbp:requires	cytochrome P450 monooxygenase activity
gptkbp:species	gptkb:Mus_musculus gptkb:Homo_sapiens
gptkbp:structure	monomeric
gptkbp:UniProtID	P16435
gptkbp:bfsParent	gptkb:cytochrome_P450_enzymes gptkb:P450C2C9 gptkb:Cytochrome_P450,_subfamily_IIIA,_polypeptide_4
gptkbp:bfsLayer	6