Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alias |
gptkb:CYP2C8
P450IIC8 cytochrome P450, family 2, subfamily C, polypeptide 8 |
| gptkbp:catalyzes |
drug metabolism
fatty acid metabolism |
| gptkbp:EC_number |
1.14.14.1
|
| gptkbp:Entrez_Gene_ID |
GC10P096285
|
| gptkbp:foundIn |
gptkb:kidney
human liver |
| gptkbp:hasPolymorphism |
gptkb:CYP2C8*2
gptkb:CYP2C8*3 gptkb:CYP2C8*4 |
| gptkbp:HGNC_ID |
2591
|
| https://www.w3.org/2000/01/rdf-schema#label |
cytochrome P450 2C8
|
| gptkbp:inducedBy |
drug-drug interactions
|
| gptkbp:inhibitedBy |
gptkb:clopidogrel
gptkb:gemfibrozil gptkb:montelukast |
| gptkbp:locatedIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_10
|
| gptkbp:memberOf |
gptkb:cytochrome_P450_superfamily
|
| gptkbp:OMIM |
601134
|
| gptkbp:PDB |
2NNI
|
| gptkbp:product |
CYP2C8 gene
|
| gptkbp:RefSeq |
NM_000770
|
| gptkbp:substrate |
gptkb:ibuprofen
gptkb:repaglinide gptkb:rosiglitazone gptkb:amodiaquine paclitaxel |
| gptkbp:UniProtID |
P10632
|
| gptkbp:bfsParent |
gptkb:CYP2C8
|
| gptkbp:bfsLayer |
6
|