|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:administered_by
|
oral tablet
topical gel
liquid suspension
|
|
gptkbp:available_on
|
gptkb:pharmaceuticals
prescription medication
|
|
gptkbp:brand
|
gptkb:Midol
gptkb:Advil
gptkb:Nurofen
gptkb:Advil_Liqui-Gels
gptkb:Motrin
gptkb:Motrin_IB
Brufen
Rufen
|
|
gptkbp:casnumber
|
15687-27-1
|
|
gptkbp:category
|
Category C
|
|
gptkbp:chemical_formula
|
C13 H18 O2
|
|
gptkbp:contraindication
|
gptkb:disease
peptic ulcer disease
severe heart failure
|
|
gptkbp:discovered_by
|
gptkb:Dr._Stewart_Adams
|
|
gptkbp:discovery_year
|
gptkb:1961
|
|
gptkbp:dosage_form
|
200-400 mg every 4-6 hours
1200 mg per day (OTC)
3200 mg per day (prescription)
|
|
gptkbp:duration
|
short-term use recommended
long-term use requires medical supervision
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:formulation
|
gptkb:cream
gptkb:tablet
gptkb:gel
suspension
injection
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ibuprofen
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
gptkb:warfarin
lithium
|
|
gptkbp:mechanism_of_action
|
inhibition of cyclooxygenase (COX) enzymes
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:side_effect
|
dizziness
headache
nausea
stomach pain
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:used_for
|
pain relief
inflammation reduction
fever reduction
|
|
gptkbp:bfsParent
|
gptkb:Painkiller
|
|
gptkbp:bfsLayer
|
5
|