|
gptkbp:instanceOf
|
gptkb:drug
leukotriene receptor antagonist
|
|
gptkbp:approvalYear
|
1998
|
|
gptkbp:approvedBy
|
gptkb:United_States
|
|
gptkbp:ATCCode
|
R03DC03
|
|
gptkbp:bioavailability
|
64%
|
|
gptkbp:brand
|
gptkb:Singulair
|
|
gptkbp:CASNumber
|
151767-02-1
|
|
gptkbp:category
|
gptkb:Essential_medicine_(WHO)
|
|
gptkbp:chemicalFormula
|
contains quinoline ring
|
|
gptkbp:compatibleWith
|
acute asthma attacks
|
|
gptkbp:contraindication
|
hypersensitivity to montelukast
|
|
gptkbp:developer
|
gptkb:Merck_&_Co.
|
|
gptkbp:drugClass
|
anti-allergic
anti-asthmatic
|
|
gptkbp:eliminationHalfLife
|
2.7–5.5 hours
|
|
gptkbp:excretion
|
bile
|
|
gptkbp:form
|
gptkb:tablet
chewable tablet
granules
|
|
gptkbp:hasMolecularFormula
|
C35H36ClNO3S
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
montelukast
|
|
gptkbp:KEGGID
|
D08123
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
leukotriene D4 receptor antagonist
|
|
gptkbp:MedlinePlusID
|
a600014
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:patentExpired
|
2012 (US)
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:prescribes
|
adults
children
|
|
gptkbp:proteinBinding
|
>99%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL411
5281040
DB00471
|
|
gptkbp:riskFactor
|
behavioral changes
suicidal thoughts
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
abdominal pain
headache
cough
neuropsychiatric effects
|
|
gptkbp:storage
|
room temperature
|
|
gptkbp:UNII
|
32U4SFZV2S
|
|
gptkbp:usedFor
|
asthma
allergic rhinitis
exercise-induced bronchoconstriction
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Singulair
|
|
gptkbp:bfsLayer
|
5
|