Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:affectsDrugMetabolism |
gptkb:ibuprofen
gptkb:repaglinide gptkb:pioglitazone gptkb:rosiglitazone paclitaxel |
| gptkbp:affectsEnzymeActivity |
altered
|
| gptkbp:aminoAcidChange |
K399R
R139K |
| gptkbp:Entrez_Gene_ID |
rs10509681
rs11572080 |
| gptkbp:hasAllele |
gptkb:CYP2C8
|
| gptkbp:hasFrequencyInAfricans |
rare
|
| gptkbp:hasFrequencyInEastAsians |
rare
|
| gptkbp:hasFrequencyInEuropeans |
~13%
|
| gptkbp:hasNucleotideChange |
1196A>G
416G>A |
| gptkbp:significance |
variable drug response
|
| gptkbp:bfsParent |
gptkb:CYP2C8
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP2C8*3
|