|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:CYP2A6
gptkb:cytochrome_P450,_family_2,_subfamily_A,_polypeptide_6
|
|
gptkbp:associatedWith
|
drug metabolism
nicotine dependence
|
|
gptkbp:biologicalProcess
|
monooxygenase activity
|
|
gptkbp:catalyzes
|
coumarin 7-hydroxylation
nicotine metabolism
oxidation of xenobiotics
|
|
gptkbp:EC_number
|
1.14.14.1
|
|
gptkbp:expressedIn
|
gptkb:cancer
liver
|
|
gptkbp:foundIn
|
humans
|
|
gptkbp:gene
|
gptkb:CYP2A6
|
|
gptkbp:hasPolymorphism
|
gptkb:CYP2A6*2
gptkb:CYP2A6*4
gptkb:CYP2A6*9
|
|
gptkbp:HGNC_ID
|
2597
|
|
gptkbp:inhibitedBy
|
gptkb:methoxsalen
gptkb:tranylcypromine
gptkb:selegiline
|
|
gptkbp:locatedIn
|
gptkb:endoplasmic_reticulum
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19q13.2
|
|
gptkbp:member
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:OMIM
|
601040
|
|
gptkbp:orthologInMouse
|
gptkb:Cyp2a5
|
|
gptkbp:substrate
|
gptkb:aflatoxin_B1
gptkb:tegafur
gptkb:coumarin
gptkb:letrozole
nicotine
|
|
gptkbp:UniProtID
|
P11509
|
|
gptkbp:bfsParent
|
gptkb:CYP2A6
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cytochrome P450 2A6
|