|
gptkbp:instance_of
|
gptkb:chemical_compound
|
|
gptkbp:bfsLayer
|
7
|
|
gptkbp:bfsParent
|
gptkb:5-fluorouracil
|
|
gptkbp:activities
|
gptkb:fragrance
|
|
gptkbp:approves
|
gptkb:China
gptkb:Japan
gptkb:Monarch
gptkb:Taiwan
|
|
gptkbp:brand
|
gptkb:UFT
Tegafur-uracil
|
|
gptkbp:can_be_used_with
|
gptkb:cisplatin
gptkb:irinotecan
gptkb:oxaliplatin
uracil
|
|
gptkbp:class
|
fluoropyrimidine
|
|
gptkbp:clinical_trial
|
Phase II
Phase III
|
|
gptkbp:composed_of
|
gptkb:chemical_compound
pharmaceutical synthesis
|
|
gptkbp:contraindication
|
pregnancy
severe renal impairment
severe liver impairment
lactation
|
|
gptkbp:developed_by
|
Taiho Pharmaceutical
|
|
gptkbp:discovered_by
|
gptkb:1980s
|
|
gptkbp:dissolved
|
soluble in water
soluble in ethanol
|
|
gptkbp:dosage_form
|
gptkb:beer
gptkb:tablet
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
tegafur
|
|
gptkbp:ingredients
|
C11 H13 F3 N2 O2
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
gptkb:phenytoin
gptkb:warfarin
|
|
gptkbp:invention
|
patented
generic available
|
|
gptkbp:is_monitored_by
|
liver function tests
complete blood count
renal function tests
|
|
gptkbp:manager
|
oral
|
|
gptkbp:marketed_as
|
gptkb:UFT
Tegafur-uracil
|
|
gptkbp:metabolism
|
gptkb:5-fluorouracil
|
|
gptkbp:side_effect
|
gptkb:fandom
fatigue
nausea
vomiting
diarrhea
thrombocytopenia
alopecia
bone marrow suppression
stomatitis
leukopenia
|
|
gptkbp:storage
|
room temperature
protected from light
|
|
gptkbp:targets
|
gptkb:healthcare_organization
|
|
gptkbp:used_in
|
gptkb:healthcare_organization
|