cytochrome P450, family 2, subfamily A, polypeptide 6
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
lung cancer risk
nicotine dependence drug response variability |
| gptkbp:encodedBy |
CYP2A6 gene
|
| gptkbp:enzymeCommissionNumber |
gptkb:EC_1.14.14.1
|
| gptkbp:family |
gptkb:cytochrome_P450
|
| gptkbp:function |
monooxygenase activity
drug metabolism nicotine metabolism |
| gptkbp:gene |
gptkb:CYP2A6
|
| gptkbp:hasPolymorphism |
gptkb:CYP2A6*2
gptkb:CYP2A6*4 gptkb:CYP2A6*9 |
| gptkbp:HGNC_ID |
2592
|
| https://www.w3.org/2000/01/rdf-schema#label |
cytochrome P450, family 2, subfamily A, polypeptide 6
|
| gptkbp:inhibitedBy |
gptkb:methoxsalen
gptkb:tranylcypromine |
| gptkbp:locatedIn |
gptkb:endoplasmic_reticulum
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19q13.2
|
| gptkbp:OMIM |
601040
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:2FDY
|
| gptkbp:polypeptide |
6
|
| gptkbp:RefSeq |
NM_000762
|
| gptkbp:subfamily |
2A
|
| gptkbp:substrate |
gptkb:aflatoxin_B1
nicotine coumarin testosterone |
| gptkbp:UniProtID |
P11509
|
| gptkbp:bfsParent |
gptkb:cytochrome_P450_2A6
|
| gptkbp:bfsLayer |
7
|