catenin (cadherin-associated protein), beta 1

URI: https://gptkb.org/entity/catenin_(cadherin-associated_protein),_beta_1
GPTKB entity
Statements (38)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:beta-catenin
gptkbp:associatedWith gptkb:medulloblastoma
colorectal cancer
hepatocellular carcinoma
gptkbp:biologicalProcess cell proliferation
embryonic development
gene transcription regulation
gptkbp:discoveredBy Rolf Kemler
gptkbp:discoveredIn 1991
gptkbp:encodedBy gptkb:CTNNB1_gene
gptkbp:Entrez_Gene_ID 1499
ENSG00000168036
gptkbp:function gptkb:Wnt_signaling_pathway
cell adhesion
gptkbp:gene gptkb:CTNNB1
gptkbp:GO gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated)
GO:0005912 (adherens junction)
GO:0008284 (positive regulation of cell proliferation)
https://www.w3.org/2000/01/rdf-schema#label catenin (cadherin-associated protein), beta 1
gptkbp:interactsWith gptkb:APC_protein
gptkb:TCF/LEF_transcription_factors
gptkb:cadherins
axin
gptkbp:locatedOnChromosome 3p22.1
gptkbp:location gptkb:cell_membrane
gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight ~88 kDa
gptkbp:OMIM 116806
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 1JDH
gptkbp:postTranslationalModification phosphorylation
ubiquitination
gptkbp:RefSeq NP_001895.1
gptkbp:UniProtID gptkb:P35222
gptkbp:bfsParent gptkb:CTNNB1
gptkbp:bfsLayer 5