catenin (cadherin-associated protein), beta 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:beta-catenin
gptkbp:associatedWith	gptkb:medulloblastoma colorectal cancer hepatocellular carcinoma
gptkbp:biologicalProcess	cell proliferation embryonic development gene transcription regulation
gptkbp:discoveredBy	Rolf Kemler
gptkbp:discoveredIn	1991
gptkbp:encodedBy	gptkb:CTNNB1_gene
gptkbp:Entrez_Gene_ID	1499 ENSG00000168036
gptkbp:function	gptkb:Wnt_signaling_pathway cell adhesion
gptkbp:gene	gptkb:CTNNB1
gptkbp:GO	gptkb:GO:0006355_(regulation_of_transcription,_DNA-templated) GO:0005912 (adherens junction) GO:0008284 (positive regulation of cell proliferation)
gptkbp:interactsWith	gptkb:APC_protein gptkb:TCF/LEF_transcription_factors gptkb:cadherins axin
gptkbp:locatedOnChromosome	3p22.1
gptkbp:location	gptkb:cell_membrane gptkb:nucleus gptkb:cytoplasm
gptkbp:molecularWeight	~88 kDa
gptkbp:OMIM	116806
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:PDB	1JDH
gptkbp:postTranslationalModification	phosphorylation ubiquitination
gptkbp:RefSeq	NP_001895.1
gptkbp:UniProtID	gptkb:P35222
gptkbp:bfsParent	gptkb:CTNNB1 gptkb:CTNNB1_gene
gptkbp:bfsLayer	8
http://www.w3.org/2000/01/rdf-schema#label	catenin (cadherin-associated protein), beta 1