Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
produces lamin C
|
| gptkbp:component |
gptkb:nuclear_lamina
|
| gptkbp:encodedBy |
gptkb:LMNA_gene
|
| gptkbp:foundIn |
gptkb:nucleus
|
| gptkbp:function |
DNA replication
chromatin organization regulation of gene expression structural support of nucleus |
| gptkbp:interactsWith |
gptkb:lamin_C
emerin lamin B nuclear envelope proteins |
| gptkbp:locale |
inner nuclear membrane
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_1q22
|
| gptkbp:molecularWeight |
~74 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:dilated_cardiomyopathy
gptkb:familial_partial_lipodystrophy gptkb:Emery-Dreifuss_muscular_dystrophy gptkb:Hutchinson-Gilford_progeria_syndrome |
| gptkbp:postTranslationalModification |
farnesylation
proteolytic cleavage |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:bfsParent |
gptkb:caspase-7
gptkb:LMNA gptkb:Caspase-6 gptkb:Caspase-7 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
lamin A
|