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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeSplicing
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produces lamin C
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gptkbp:component
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gptkb:nuclear_lamina
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gptkbp:encodedBy
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gptkb:LMNA_gene
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gptkbp:foundIn
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gptkb:nucleus
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gptkbp:function
|
DNA replication
chromatin organization
regulation of gene expression
structural support of nucleus
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https://www.w3.org/2000/01/rdf-schema#label
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lamin A
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gptkbp:interactsWith
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gptkb:lamin_C
emerin
lamin B
nuclear envelope proteins
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gptkbp:locale
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inner nuclear membrane
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gptkbp:locatedOnChromosome
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gptkb:chromosome_1q22
|
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gptkbp:molecularWeight
|
~74 kDa
|
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gptkbp:mutationAssociatedWith
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gptkb:dilated_cardiomyopathy
gptkb:familial_partial_lipodystrophy
gptkb:Emery-Dreifuss_muscular_dystrophy
gptkb:Hutchinson-Gilford_progeria_syndrome
|
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gptkbp:postTranslationalModification
|
farnesylation
proteolytic cleavage
|
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gptkbp:species
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gptkb:Mus_musculus
gptkb:Homo_sapiens
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gptkbp:bfsParent
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gptkb:caspase-7
gptkb:LMNA_gene
gptkb:LMNA
gptkb:Caspase-6
gptkb:Caspase-7
gptkb:Hutchinson-Gilford_progeria_syndrome
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gptkbp:bfsLayer
|
8
|