|
gptkbp:instanceOf
|
gptkb:protein
gptkb:G_protein-coupled_receptor
|
|
gptkbp:abbreviation
|
CB2
|
|
gptkbp:activatedBy
|
gptkb:endocannabinoids
synthetic cannabinoids
phytocannabinoids
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:encoded_in
|
gptkb:human_chromosome_1
|
|
gptkbp:Entrez_Gene_ID
|
1269
|
|
gptkbp:expressedIn
|
peripheral nervous system
immune cells
|
|
gptkbp:foundIn
|
gptkb:tonsils
gptkb:bone
gptkb:B_cells
gptkb:T_cells
gptkb:thymus
gptkb:mast_cells
gptkb:keratinocytes
gptkb:microglia
heart
gastrointestinal tract
liver
spleen
adipose tissue
pancreas
immune system
macrophages
peripheral tissues
monocytes
neutrophils
brain (low levels)
|
|
gptkbp:function
|
pain modulation
neuroprotection
modulation of immune response
inhibition of cytokine release
regulation of inflammation
|
|
gptkbp:gene
|
gptkb:CNR2
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:2159
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
cannabinoid receptor 2
|
|
gptkbp:OMIM
|
605051
|
|
gptkbp:opposedBy
|
gptkb:AM630
gptkb:SR144528
|
|
gptkbp:relatedTo
|
gptkb:cannabinoid_receptor_1
|
|
gptkbp:structure
|
seven transmembrane domains
|
|
gptkbp:target
|
gptkb:tetrahydrocannabinol
synthetic cannabinoids
cannabidiol
cannabinol
|
|
gptkbp:UniProtID
|
gptkb:P34972
|
|
gptkbp:bfsParent
|
gptkb:cannabinoid_receptor_1
|
|
gptkbp:bfsLayer
|
7
|