|
gptkbp:instanceOf
|
cell cluster
endocrine tissue
|
|
gptkbp:alphaCellFunction
|
produce glucagon
|
|
gptkbp:alsoKnownAs
|
gptkb:islets_of_Langerhans
|
|
gptkbp:betaCellFunction
|
produce insulin
|
|
gptkbp:deltaCellFunction
|
produce somatostatin
|
|
gptkbp:discoveredBy
|
gptkb:Paul_Langerhans
|
|
gptkbp:discoveredIn
|
1869
|
|
gptkbp:dysregulationAssociatedWith
|
gptkb:diabetes_mellitus
gptkb:hypoglycemia
hyperinsulinism
|
|
gptkbp:epsilonCellFunction
|
produce ghrelin
|
|
gptkbp:function
|
regulate blood glucose
|
|
gptkbp:hasType
|
PP cell
alpha cell
beta cell
delta cell
epsilon cell
|
|
gptkbp:histology
|
lighter staining than exocrine pancreas
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pancreatic islets
|
|
gptkbp:locatedIn
|
pancreas
|
|
gptkbp:numberInHumanBody
|
about 1 million
|
|
gptkbp:percentageOfPancreas
|
1-2%
|
|
gptkbp:PPCellFunction
|
produce pancreatic polypeptide
|
|
gptkbp:relatedTo
|
endocrine system
glucose homeostasis
|
|
gptkbp:secretes
|
gptkb:glucagon
gptkb:insulin
gptkb:somatostatin
ghrelin
pancreatic polypeptide
|
|
gptkbp:significance
|
target for islet transplantation
|
|
gptkbp:vascularized
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Chromogranin_A
|
|
gptkbp:bfsLayer
|
6
|