adrenoceptor beta 2, surface

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:beta-2_adrenergic_receptor
gptkbp:associatedWith	asthma heart failure chronic obstructive pulmonary disease
gptkbp:discoveredBy	gptkb:Robert_Lefkowitz
gptkbp:expressedIn	gptkb:skeletal_muscle liver smooth muscle lung tissue
gptkbp:family	gptkb:adrenergic_receptor_family
gptkbp:function	activates adenylate cyclase via Gs protein binds epinephrine and norepinephrine
gptkbp:gene	gptkb:ADRB2
gptkbp:GO	GO:0004930
gptkbp:HGNC_ID	gptkb:HGNC:286
gptkbp:internalizedBy	beta-arrestin
gptkbp:length	413
gptkbp:locatedOnChromosome	5q31-q32
gptkbp:modulatedBy	beta blockers antagonists agonists inverse agonists partial agonists
gptkbp:molecularWeight	46 kDa
gptkbp:OMIM	109690
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Rattus_norvegicus
gptkbp:PDB	gptkb:2RH1
gptkbp:phosphorylates	gptkb:protein_kinase_A G protein-coupled receptor kinases
gptkbp:recipient	gptkb:G_protein-coupled_receptor
gptkbp:role	glycogenolysis vasodilation smooth muscle relaxation bronchodilation
gptkbp:species	gptkb:Homo_sapiens
gptkbp:structureType	7 transmembrane domains
gptkbp:subfamily	beta-adrenergic receptor subfamily
gptkbp:targetOfDrug	gptkb:formoterol gptkb:salmeterol gptkb:albuterol gptkb:isoproterenol terbutaline
gptkbp:type	gptkb:cAMP_pathway
gptkbp:UniProtID	gptkb:P07550
gptkbp:bfsParent	gptkb:ADRB2
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	adrenoceptor beta 2, surface