|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:Wnt-3a
gptkb:wingless-type_MMTV_integration_site_family,_member_3A
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
osteosarcoma
developmental processes
|
|
gptkbp:discoveredBy
|
1990s
|
|
gptkbp:encodes
|
gptkb:Wnt-3a_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000108379
89780
|
|
gptkbp:expressedIn
|
embryonic tissues
adult tissues
|
|
gptkbp:function
|
cell proliferation
cell migration
stem cell maintenance
cell polarity
regulation of cell fate and patterning during embryogenesis
|
|
gptkbp:gene
|
gptkb:WNT3A
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
12782
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT3A
|
|
gptkbp:involves
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:length
|
352
|
|
gptkbp:locatedOnChromosome
|
1q42.13
|
|
gptkbp:member
|
gptkb:Wnt_gene_family
|
|
gptkbp:molecularWeight
|
39 kDa
|
|
gptkbp:mutationAssociatedWith
|
developmental disorders
|
|
gptkbp:OMIM
|
606359
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt3a
|
|
gptkbp:pathway
|
canonical Wnt/β-catenin signaling
non-canonical Wnt signaling
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_family
secreted glycoprotein
|
|
gptkbp:recipient
|
gptkb:Frizzled_family_receptors
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
gene transcription
β-catenin stabilization
|
|
gptkbp:relatedTo
|
neural development
hematopoiesis
limb development
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:UniProtID
|
gptkb:P56704
|
|
gptkbp:bfsParent
|
gptkb:TCF/LEF
gptkb:Wnt_ligands
gptkb:WNT4
|
|
gptkbp:bfsLayer
|
7
|