Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
signaling molecule |
| gptkbp:actsOn |
canonical Wnt pathway
non-canonical Wnt pathway |
| gptkbp:binds |
gptkb:Frizzled_receptors
gptkb:LRP5/6_co-receptors |
| gptkbp:discoveredIn |
1982
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
developmental disorders bone diseases |
| gptkbp:encodedBy |
gptkb:WNT_genes
|
| gptkbp:example |
gptkb:WNT3A
gptkb:WNT1 gptkb:WNT10B gptkb:WNT5A gptkb:WNT7A |
| gptkbp:foundIn |
animals
humans |
| https://www.w3.org/2000/01/rdf-schema#label |
Wnt ligands
|
| gptkbp:involvedIn |
gptkb:Wnt_signaling_pathway
|
| gptkbp:namedAfter |
Wingless (Drosophila) and Int-1 (mouse)
|
| gptkbp:numberOfMembers |
19 in humans
|
| gptkbp:postTranslationalModification |
palmitoylation
|
| gptkbp:regulates |
cell proliferation
embryonic development cell migration cell fate determination stem cell maintenance cell polarity |
| gptkbp:secretes |
Wnt-producing cells
|
| gptkbp:bfsParent |
gptkb:Wnt_signaling_pathway
gptkb:Catenin_beta-1 |
| gptkbp:bfsLayer |
6
|