Vascular Endothelial Growth Factor Receptor 1

URI: https://gptkb.org/entity/Vascular_Endothelial_Growth_Factor_Receptor_1
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName gptkb:FLT1
Fms-related tyrosine kinase 1
gptkbp:associatedWith gptkb:cancer
pre-eclampsia
gptkbp:biologicalProcess receptor tyrosine kinase activity
gptkbp:discoveredBy gptkb:Napoleone_Ferrara
gptkbp:domain immunoglobulin-like domain
tyrosine kinase domain
gptkbp:encodedBy gptkb:FLT1_gene
gptkbp:Entrez_Gene_ID ENSG00000102755
gptkbp:expressedIn endothelial cells
monocytes
gptkbp:function regulates angiogenesis
binds vascular endothelial growth factors
involved in vasculogenesis
gptkbp:hasIsoform soluble FLT1 (sFLT1)
gptkbp:HGNC_ID 3763
https://www.w3.org/2000/01/rdf-schema#label Vascular Endothelial Growth Factor Receptor 1
gptkbp:ligand gptkb:VEGF-A
gptkb:VEGF-B
gptkb:placental_growth_factor_(PlGF)
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome gptkb:chromosome_13q12
gptkbp:OMIM 165070
gptkbp:PDB 3HNG
gptkbp:species gptkb:Homo_sapiens
gptkbp:UniProtID P17948
gptkbp:bfsParent gptkb:VEGFR1
gptkbp:bfsLayer 6