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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alternativeName
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gptkb:Neurotrophic_tyrosine_kinase_receptor_type_1_(mouse)
Ntrk1 protein (mouse)
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gptkbp:biologicalProcess
|
gptkb:neurotrophin_signaling_pathway
cell survival
neuronal differentiation
transmembrane receptor protein tyrosine kinase activity
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gptkbp:cellularComponent
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gptkb:plasma_membrane
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gptkbp:domain
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immunoglobulin-like domain
leucine-rich repeat domain
tyrosine kinase domain
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gptkbp:encodedBy
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gptkb:Ntrk1_(mouse)
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gptkbp:Entrez_Gene_ID
|
18174
|
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gptkbp:expressedIn
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gptkb:nervous_system
sensory neurons
sympathetic neurons
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gptkbp:function
|
gptkb:receptor_tyrosine_kinase
gptkb:nerve_growth_factor_receptor
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TrkA (mouse)
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gptkbp:involvedIn
|
apoptosis regulation
pain perception
sympathetic nervous system development
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gptkbp:length
|
796 amino acids
|
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gptkbp:ligand
|
gptkb:nerve_growth_factor_(NGF)
|
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gptkbp:locatedOnChromosome
|
gptkb:mouse_chromosome_3
|
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gptkbp:molecularWeight
|
87 kDa
|
|
gptkbp:mutationAssociatedWith
|
defective neuronal development
impaired pain sensation
|
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gptkbp:organism
|
gptkb:Mus_musculus
|
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gptkbp:orthologIn
|
gptkb:TrkA_(human)
|
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gptkbp:pathway
|
gptkb:neurotrophin_signaling_pathway
apoptosis regulation
axon guidance
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gptkbp:PDB
|
4F0I
|
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gptkbp:postTranslationalModification
|
phosphorylation
|
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gptkbp:reviewedBy
|
gptkb:NCBI_Gene
gptkb:UniProt
gptkb:MGI_(Mouse_Genome_Informatics)
|
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gptkbp:subunit
|
monomer
dimer (upon ligand binding)
|
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gptkbp:type
|
gptkb:MAPK_pathway
gptkb:PI3K-Akt_pathway
gptkb:PLC-gamma_pathway
|
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gptkbp:UniProtID
|
Q3UFB7
|
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gptkbp:bfsParent
|
gptkb:NTRK1
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gptkbp:bfsLayer
|
7
|