Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
signaling molecule
|
| gptkbp:activatedBy |
gptkb:receptor_tyrosine_kinases
growth factors antigen receptors |
| gptkbp:cause |
production of diacylglycerol (DAG)
production of inositol trisphosphate (IP3) |
| gptkbp:component |
gptkb:PLC-gamma1
PLC-gamma2 |
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
autoimmune diseases |
| gptkbp:foundIn |
mammalian cells
|
| gptkbp:hasRole |
cell differentiation
cell proliferation immune cell signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
PLC-gamma pathway
|
| gptkbp:involves |
hydrolysis of PIP2
phospholipase C-gamma |
| gptkbp:result |
release of intracellular calcium
activation of protein kinase C (PKC) |
| gptkbp:bfsParent |
gptkb:TrkA_(mouse)
|
| gptkbp:bfsLayer |
8
|