Tissue inhibitor of metalloproteinases 2
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:TIMP2
|
| gptkbp:encodedBy |
gptkb:TIMP2_gene
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:foundIn |
extracellular matrix
|
| gptkbp:function |
inhibits matrix metalloproteinases
|
| https://www.w3.org/2000/01/rdf-schema#label |
Tissue inhibitor of metalloproteinases 2
|
| gptkbp:inhibitedBy |
gptkb:MMP2
gptkb:MMP9 |
| gptkbp:locatedOnChromosome |
chromosome 17q25
|
| gptkbp:molecularWeight |
24 kDa
|
| gptkbp:OMIM |
188825
|
| gptkbp:regulates |
cell proliferation
angiogenesis extracellular matrix composition |
| gptkbp:relatedTo |
gptkb:TIMP1
gptkb:TIMP3 gptkb:TIMP4 |
| gptkbp:role |
gptkb:cardiovascular_disease
cancer progression fibrosis |
| gptkbp:structure |
contains N-terminal and C-terminal domains
|
| gptkbp:UniProtID |
P16035
|
| gptkbp:bfsParent |
gptkb:TIMP2
|
| gptkbp:bfsLayer |
7
|