Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:discoveredBy |
1996
|
| gptkbp:encodedBy |
gptkb:TIMP4_gene
|
| gptkbp:Entrez_Gene_ID |
7079
ENSG00000105879 |
| gptkbp:expressedIn |
gptkb:skeletal_muscle
gptkb:placenta gptkb:testis brain heart pancreas |
| gptkbp:family |
gptkb:TIMP_family
|
| gptkbp:fullName |
gptkb:Tissue_inhibitor_of_metalloproteinases_4
|
| gptkbp:function |
inhibits matrix metalloproteinases
|
| gptkbp:gene |
gptkb:TIMP4
|
| gptkbp:HGNC_ID |
gptkb:HGNC:11822
|
| https://www.w3.org/2000/01/rdf-schema#label |
TIMP4
|
| gptkbp:inhibitedBy |
gptkb:MMP14
gptkb:MMP2 gptkb:MMP9 |
| gptkbp:locatedOnChromosome |
3p25
|
| gptkbp:molecularWeight |
22 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:relatedTo |
cardiac function
extracellular matrix remodeling inhibition of angiogenesis |
| gptkbp:significance |
implicated in cancer progression
implicated in cardiovascular disease |
| gptkbp:structure |
contains N-terminal and C-terminal domains
|
| gptkbp:UniProtID |
Q99727
|
| gptkbp:bfsParent |
gptkb:EGR1
|
| gptkbp:bfsLayer |
6
|