|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
KAT5
Tat-interactive protein, 60kDa
|
|
gptkbp:amendedBy
|
gptkb:p53
gptkb:histone_H2A
gptkb:histone_H4
ATM
histone H2AX
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
|
|
gptkbp:component
|
gptkb:nucleus
chromatin
Tip60 complex
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodedBy
|
KAT5 gene
|
|
gptkbp:Entrez_Gene_ID
|
10524
|
|
gptkbp:enzymeCommissionNumber
|
EC 2.3.1.48
|
|
gptkbp:function
|
DNA repair
apoptosis regulation
transcription regulation
chromatin remodeling
histone acetyltransferase activity
histone acetyltransferase
|
|
gptkbp:GOProcess
|
DNA repair
chromatin organization
regulation of transcription, DNA-templated
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tip60
|
|
gptkbp:interactsWith
|
gptkb:Mdm2
gptkb:c-Myc
gptkb:E2F1
gptkb:p53
ATM
TRRAP
|
|
gptkbp:locale
|
gptkb:nucleus
|
|
gptkbp:locatedOnChromosome
|
11q13.1
|
|
gptkbp:memberOf
|
gptkb:MYST_family
|
|
gptkbp:molecularWeight
|
~60 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster
|
|
gptkbp:PDB
|
2EKO
2OU2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:regulates
|
apoptosis
gene expression
cell cycle
DNA double-strand break repair
|
|
gptkbp:UniProtID
|
Q92993
|
|
gptkbp:bfsParent
|
gptkb:Histone_acetyltransferase
|
|
gptkbp:bfsLayer
|
7
|