Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:DR5
gptkb:CD262 gptkb:TNFRSF10B KILLER TRICK2 |
| gptkbp:binds |
gptkb:TRAIL
|
| gptkbp:cellSurfaceMarker |
gptkb:CD262
|
| gptkbp:contains |
death domain
|
| gptkbp:discoveredIn |
late 1990s
|
| gptkbp:encodedBy |
gptkb:TNFRSF10B_gene
|
| gptkbp:Entrez_Gene_ID |
8795
ENSG00000120889 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
induces apoptosis
|
| gptkbp:HGNC_ID |
11905
|
| https://www.w3.org/2000/01/rdf-schema#label |
TRAIL receptor 2
|
| gptkbp:interactsWith |
gptkb:FADD
gptkb:caspase-8 |
| gptkbp:involvedIn |
immune response
cell death signaling pathway |
| gptkbp:locatedOnChromosome |
chromosome 8
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:OMIM |
603639
|
| gptkbp:PDB |
1D4V
|
| gptkbp:relatedTo |
gptkb:cancer
autoimmune diseases apoptosis regulation |
| gptkbp:structureType |
transmembrane protein
|
| gptkbp:UniProtID |
gptkb:O14763
|
| gptkbp:bfsParent |
gptkb:DR5
|
| gptkbp:bfsLayer |
7
|