Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:DR5
gptkb:CD262 gptkb:TRAIL_receptor_2 KILLER TRICK2 |
| gptkbp:associatedWith |
gptkb:cancer
apoptosis regulation |
| gptkbp:contains |
death domain
|
| gptkbp:encodes |
Tumor necrosis factor receptor superfamily member 10B
|
| gptkbp:Entrez_Gene_ID |
8795
ENSG00000120889 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
mediates apoptosis
|
| gptkbp:HGNC_ID |
11905
|
| https://www.w3.org/2000/01/rdf-schema#label |
TNFRSF10B gene
|
| gptkbp:locatedOnChromosome |
chromosome 8
8p21.3 |
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_receptor_superfamily
|
| gptkbp:mutationAssociatedWith |
drug resistance
tumor progression |
| gptkbp:OMIM |
603639
|
| gptkbp:product |
gptkb:TRAIL-R2
|
| gptkbp:receptorFor |
TRAIL (TNFSF10)
|
| gptkbp:regulates |
cell death signaling pathways
|
| gptkbp:transmembraneDomains |
true
|
| gptkbp:UniProtID |
gptkb:O14763
|
| gptkbp:bfsParent |
gptkb:DR5
|
| gptkbp:bfsLayer |
7
|