Statements (41)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:biological_pathway
|
| gptkbp:activatedBy |
DNA damage
oncogenic stress |
| gptkbp:alsoKnownAs |
p53 pathway
|
| gptkbp:describedBy |
KEGG: hsa04115
Reactome: R-HSA-69541 |
| gptkbp:dysfunctionLeadsTo |
gptkb:cancer
genomic instability |
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:hasKeyGene |
gptkb:CDKN1A
gptkb:MDMX gptkb:BAX gptkb:NOXA gptkb:PUMA gptkb:MDM2 gptkb:GADD45A gptkb:TP53 |
| gptkbp:involves |
gptkb:CDKN1A
gptkb:BAX gptkb:NOXA gptkb:PUMA gptkb:MDM2 gptkb:GADD45A gptkb:TP53 |
| gptkbp:namedAfter |
gptkb:TP53_gene
|
| gptkbp:negativelyRegulatedBy |
gptkb:MDMX
gptkb:MDM2 |
| gptkbp:partOf |
cellular response to stress
tumor suppressor pathways |
| gptkbp:regulates |
apoptosis
DNA repair senescence cell cycle arrest |
| gptkbp:bfsParent |
gptkb:TP53TG10
gptkb:TP53TG20 gptkb:TP53TG22 gptkb:TP53TG23 gptkb:TP53TG27 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
TP53 pathway
|