|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:ATAR
gptkb:Herpesvirus_entry_mediator
TR2
HVEM
|
|
gptkbp:associatedWith
|
gptkb:cancer
leukemia
autoimmune diseases
|
|
gptkbp:binds
|
gptkb:BTLA
gptkb:CD160
gptkb:LIGHT_(TNFSF14)
LTα
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
TNFRSF14 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000163599
8764
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:T_cells
dendritic cells
lymphoid tissues
monocytes
|
|
gptkbp:fullName
|
Tumor necrosis factor receptor superfamily member 14
|
|
gptkbp:function
|
immune regulation
apoptosis regulation
T cell costimulation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasCytoplasmicDomain
|
true
|
|
gptkbp:hasExtracellularDomain
|
true
|
|
gptkbp:HGNC_ID
|
11910
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TNFRSF14
|
|
gptkbp:involvedIn
|
immune checkpoint regulation
herpesvirus entry
|
|
gptkbp:length
|
283
|
|
gptkbp:locatedOnChromosome
|
1p36.32
|
|
gptkbp:memberOf
|
gptkb:tumor_necrosis_factor_receptor_superfamily
|
|
gptkbp:molecularWeight
|
31 kDa
|
|
gptkbp:OMIM
|
602746
|
|
gptkbp:orthologInMouse
|
Tnfrsf14
|
|
gptkbp:regulates
|
T cell activation
inflammatory response
B cell function
|
|
gptkbp:target
|
immunotherapy
therapeutic antibodies
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
Q92956
|
|
gptkbp:bfsParent
|
gptkb:TNFRSF
gptkb:TRAF5
|
|
gptkbp:bfsLayer
|
8
|