Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
TNFSF14
CD258 homologous to lymphotoxins, exhibits inducible expression, competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes |
| gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases inflammatory diseases |
| gptkbp:binds |
DcR3 (decoy receptor 3)
HVEM (TNFRSF14) LTβR (lymphotoxin beta receptor) |
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodedBy |
TNFSF14 gene
|
| gptkbp:Entrez_Gene_ID |
8740
ENSG00000125726 |
| gptkbp:expressedIn |
gptkb:natural_killer_cells
activated T cells immature dendritic cells |
| gptkbp:function |
induces apoptosis
regulates immune response costimulatory molecule for T cells |
| gptkbp:geneLocationEnd |
6,186,013
|
| gptkbp:geneLocationStart |
6,181,964
|
| gptkbp:geneStrand |
plus
|
| gptkbp:HGNC_ID |
11941
|
| https://www.w3.org/2000/01/rdf-schema#label |
LIGHT (TNFSF14)
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19p13.3
|
| gptkbp:memberOf |
gptkb:tumor_necrosis_factor_superfamily
|
| gptkbp:molecularWeight |
29 kDa (precursor)
|
| gptkbp:OMIM |
603595
|
| gptkbp:orthologInMouse |
Tnfsf14
|
| gptkbp:structure |
type II transmembrane protein
|
| gptkbp:UniProtID |
O43557
|
| gptkbp:bfsParent |
gptkb:CD270
|
| gptkbp:bfsLayer |
8
|