Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:associatedWith |
gptkb:Bacteria
gptkb:Crohn's_disease inflammatory bowel disease |
| gptkbp:discoveredBy |
gptkb:Bruce_Beutler
|
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodedBy |
gptkb:TLR5_gene
|
| gptkbp:Entrez_Gene_ID |
7100
ENSG00000185291 |
| gptkbp:expressedIn |
dendritic cells
monocytes epithelial cells |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:fullName |
gptkb:Toll-like_receptor_5
|
| gptkbp:function |
activates innate immune response
recognizes bacterial flagellin |
| gptkbp:GO_term |
GO:0006954
GO:0002224 |
| https://www.w3.org/2000/01/rdf-schema#label |
TLR5
|
| gptkbp:ligand |
flagellin
|
| gptkbp:locatedOnChromosome |
1q41-q42
|
| gptkbp:location |
cell surface
|
| gptkbp:memberOf |
gptkb:Toll-like_receptor_family
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:pathway |
gptkb:NF-kappaB_signaling_pathway
|
| gptkbp:PDB |
3J0A
|
| gptkbp:RefSeq |
NM_003268
|
| gptkbp:UniProtID |
O60602
|
| gptkbp:bfsParent |
gptkb:Toll-like_receptors
|
| gptkbp:bfsLayer |
7
|