TGF-beta superfamily receptors
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
gptkb:TGF-beta_superfamily_ligands
|
| gptkbp:contains |
serine/threonine kinase domain
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:example |
gptkb:ENG
gptkb:TGFBR2 gptkb:BMPR1A gptkb:BMPR2 gptkb:TGFBR1 ACVR1 ACVR2A |
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
TGF-beta superfamily receptors
|
| gptkbp:includes |
type I receptors
type II receptors type III receptors |
| gptkbp:involvedIn |
apoptosis
differentiation embryonic development cell growth regulation immune regulation |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:cardiovascular_disease fibrosis |
| gptkbp:relatedTo |
Smad proteins
|
| gptkbp:subclassOf |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:bfsParent |
gptkb:ENG_gene
|
| gptkbp:bfsLayer |
7
|