TGF-beta superfamily ligands
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:binds |
TGF-beta receptors
|
| gptkbp:contains |
cysteine knot motif
|
| gptkbp:discoveredIn |
1980s
|
| gptkbp:evolutionarilyConserved |
yes
|
| gptkbp:foundIn |
animals
humans |
| gptkbp:function |
cell differentiation
embryonic development cell growth regulation apoptosis regulation |
| https://www.w3.org/2000/01/rdf-schema#label |
TGF-beta superfamily ligands
|
| gptkbp:includes |
gptkb:Nodal
gptkb:TGF-beta Activin Anti-Müllerian hormone Bone morphogenetic proteins Growth differentiation factors |
| gptkbp:partOf |
gptkb:TGF-beta_superfamily
|
| gptkbp:pathway |
gptkb:SMAD_pathway
|
| gptkbp:proteinFamily |
gptkb:GDF
gptkb:BMP gptkb:TGFB gptkb:AMH INHBA |
| gptkbp:relatedTo |
gptkb:cancer
immune regulation fibrosis |
| gptkbp:structure |
dimeric proteins
|
| gptkbp:bfsParent |
gptkb:activin_receptor-like_kinase_1
gptkb:Reblozyl |
| gptkbp:bfsLayer |
7
|