|
gptkbp:instanceOf
|
gptkb:protein
growth factor
|
|
gptkbp:abbreviation
|
Transforming growth factor alpha
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
colorectal cancer
|
|
gptkbp:binds
|
gptkb:epidermal_growth_factor_receptor
|
|
gptkbp:category
|
signaling molecule
cytokine
human protein
growth factor family
|
|
gptkbp:discoveredBy
|
DeLarco and Todaro
|
|
gptkbp:discoveredIn
|
1978
|
|
gptkbp:encodedBy
|
gptkb:TGFA_gene
|
|
gptkbp:foundIn
|
humans
other mammals
|
|
gptkbp:fullName
|
Transforming growth factor alpha
|
|
gptkbp:function
|
stimulates cell proliferation
induces epithelial development
|
|
gptkbp:gene
|
gptkb:TGFA
|
|
gptkbp:HGNC_ID
|
11767
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TGFα
|
|
gptkbp:locatedOnChromosome
|
2p13.3
|
|
gptkbp:OMIM
|
190170
|
|
gptkbp:recipient
|
gptkb:EGFR
|
|
gptkbp:relatedTo
|
gptkb:EGF
|
|
gptkbp:role
|
embryonic development
wound healing
cancer progression
|
|
gptkbp:secretes
|
gptkb:keratinocytes
neurons
macrophages
various epithelial cells
|
|
gptkbp:structure
|
polypeptide
|
|
gptkbp:UniProtID
|
gptkb:P01135
|
|
gptkbp:bfsParent
|
gptkb:TGF-alpha
|
|
gptkbp:bfsLayer
|
7
|