Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
beta-lactamase
|
| gptkbp:discoveredBy |
Patricia M. Richmond
|
| gptkbp:discoveredIn |
1963
|
| gptkbp:encodedBy |
blaTEM gene
|
| gptkbp:enzymeCommissionNumber |
EC 3.5.2.6
|
| gptkbp:foundIn |
gptkb:Bacteria
other Gram-negative bacteria |
| https://www.w3.org/2000/01/rdf-schema#label |
TEM-1
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam tazobactam |
| gptkbp:locatedOnChromosome |
chromosomal band
plasmid |
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:molecularWeight |
29 kDa
|
| gptkbp:namedAfter |
Temoniera patient
|
| gptkbp:resistantTo |
gptkb:antibiotic
gptkb:ampicillin |
| gptkbp:significance |
antibiotic resistance
|
| gptkbp:structure |
monomeric protein
|
| gptkbp:substrate |
gptkb:beta-lactam_antibiotics
|
| gptkbp:bfsParent |
gptkb:SHV-1
gptkb:TEM_beta-lactamase |
| gptkbp:bfsLayer |
8
|