|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:administeredBy
|
oral
intramuscular
intravenous
|
|
gptkbp:ATCCode
|
gptkb:J01CA01
|
|
gptkbp:CASNumber
|
gptkb:69-53-4
|
|
gptkbp:chemicalFormula
|
gptkb:C16H19N3O4S
|
|
gptkbp:combines
|
gptkb:clavulanic_acid
gptkb:sulbactam
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:discoveredBy
|
gptkb:Beecham_Group
|
|
gptkbp:eliminationHalfLife
|
1-1.5 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ampicillin
|
|
gptkbp:introducedIn
|
1961
|
|
gptkbp:KEGGID
|
gptkb:D00208
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:meltingPoint
|
209-212°C
|
|
gptkbp:molecularWeight
|
349.4 g/mol
|
|
gptkbp:notEffectiveAgainst
|
gptkb:Pseudomonas_aeruginosa
gptkb:Klebsiella_species
gptkb:methicillin-resistant_Staphylococcus_aureus_(MRSA)
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL29
gptkb:DB00415
6249
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
allergic reaction
rash
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:treatment
|
gptkb:sinusitis
gptkb:Enterococcus_infection
gptkb:Escherichia_coli_infection
gptkb:Haemophilus_influenzae_infection
gptkb:Listeria_monocytogenes_infection
gptkb:Proteus_mirabilis_infection
gptkb:Salmonella_infection
gptkb:Shigella_infection
meningitis
sepsis
endocarditis
urinary tract infections
gonorrhea
gastrointestinal infections
otitis media
respiratory tract infections
|
|
gptkbp:UNII
|
7C5697DR9X
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:antibiotic
gptkb:Penicillin
|
|
gptkbp:bfsLayer
|
5
|