|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:TAO2
gptkb:Thousand_And_One_Amino_Acid_Protein_Kinase_2
gptkb:MAP3K17
|
|
gptkbp:associatedWith
|
gptkb:autism_spectrum_disorder
neurodevelopmental disorders
|
|
gptkbp:discoveredBy
|
gptkb:Yoshida_et_al.
|
|
gptkbp:discoveredIn
|
2000
|
|
gptkbp:encodes
|
gptkb:Serine/threonine-protein_kinase_TAO2
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000162670
57551
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
|
|
gptkbp:fullName
|
gptkb:TAO_kinase_2
|
|
gptkbp:function
|
protein kinase activity
regulation of MAPK cascade
regulation of cytoskeleton organization
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
GO:0004672
GO:0006468
GO:0007254
|
|
gptkbp:HGNC_ID
|
HGNC:19162
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TAOK2
|
|
gptkbp:interactsWith
|
gptkb:MAP2K3
gptkb:MAP2K6
gptkb:TAOK1
gptkb:TAOK3
|
|
gptkbp:locatedOnChromosome
|
16
|
|
gptkbp:location
|
gptkb:16p11.2
|
|
gptkbp:molecularWeight
|
138 kDa
|
|
gptkbp:mutationAssociatedWith
|
alters dendrite development
impairs neuronal migration
|
|
gptkbp:numberOfExons
|
20
|
|
gptkbp:OMIM
|
613199
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Taok2
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase signaling cascade
|
|
gptkbp:phosphorylates
|
gptkb:MAP2K3
gptkb:MAP2K6
|
|
gptkbp:proteinFamily
|
gptkb:STE20_family
|
|
gptkbp:RefSeq
|
NM_016151
NP_057364
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:Golgi_apparatus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9UL54
|
|
gptkbp:bfsParent
|
gptkb:16p11.2
|
|
gptkbp:bfsLayer
|
6
|