|
gptkbp:instanceOf
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gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:MAP3K16
PSK2
TAO1
Thousand And One Amino Acid Kinase 1
|
|
gptkbp:associatedWith
|
neurodevelopmental disorder with epilepsy
|
|
gptkbp:biologicalProcess
|
signal transduction
protein kinase activity
stress-activated protein kinase signaling cascade
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:Golgi_apparatus
gptkb:cytoplasm
|
|
gptkbp:discoveredBy
|
Yasuda J et al.
|
|
gptkbp:discoveredIn
|
2001
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000162670
57551
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
heart
liver
|
|
gptkbp:fullName
|
TAO kinase 1
|
|
gptkbp:function
|
cell cycle regulation
regulation of apoptosis
serine/threonine-protein kinase activity
regulation of MAPK cascade
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:TAOK1
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TAOK1
|
|
gptkbp:interactsWith
|
gptkb:14-3-3_proteins
MAPK pathway proteins
|
|
gptkbp:length
|
1001
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q11.2
17
|
|
gptkbp:molecularWeight
|
112 kDa
|
|
gptkbp:OMIM
|
606742
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Taok1
|
|
gptkbp:PDB
|
2J5J
|
|
gptkbp:phosphorylates
|
gptkb:MAP2K3
gptkb:MAP2K6
gptkb:MAPK14
gptkb:MAPK8
|
|
gptkbp:postTranslationalModification
|
phosphorylation
autophosphorylation
|
|
gptkbp:regulates
|
microtubule dynamics
neuronal development
cell morphology
|
|
gptkbp:UniProtID
|
Q7L7X3
|
|
gptkbp:bfsParent
|
gptkb:chromosome_17
|
|
gptkbp:bfsLayer
|
6
|