|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:TAOK2
thousand and one amino acid protein kinase 2
|
|
gptkbp:associatedWith
|
gptkb:autism_spectrum_disorder
neurodevelopmental disorders
|
|
gptkbp:discoveredBy
|
gptkb:Yoshida_et_al.
|
|
gptkbp:discoveredIn
|
2000
|
|
gptkbp:domain
|
protein kinase domain
coiled-coil domain
|
|
gptkbp:EC_number
|
2.7.11.1
|
|
gptkbp:encodedBy
|
TAOK2 gene
|
|
gptkbp:Entrez_Gene_ID
|
57551
ENSG00000103496
|
|
gptkbp:expressedIn
|
gptkb:testis
brain
heart
liver
|
|
gptkbp:function
|
serine/threonine-protein kinase activity
|
|
gptkbp:hasIsoform
|
TAOK2 alpha
TAOK2 beta
|
|
gptkbp:HGNC_ID
|
HGNC:19144
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TAO kinase 2
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
gptkb:16q24.3
|
|
gptkbp:molecularWeight
|
138 kDa
|
|
gptkbp:mutationAssociatedWith
|
epilepsy
intellectual disability
|
|
gptkbp:OMIM
|
610046
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:PDB
|
2J8G
|
|
gptkbp:phosphorylates
|
gptkb:MAP2K3
gptkb:MAP2K6
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NP_055661.2
|
|
gptkbp:regulates
|
cytoskeleton organization
microtubule dynamics
neuronal development
dendrite development
|
|
gptkbp:UniProtID
|
Q9UL54
|
|
gptkbp:bfsParent
|
gptkb:TAOK2
|
|
gptkbp:bfsLayer
|
7
|